New Stem Cell Research Aims to Stop Boys Losing Fertility after Childhood Cancer Treatment

Earlier research has indeed shown that it was possible to perform a transplant of sperm stem cells from donors into the testes of infertile mice, thus restoring their fertility. However, the testes of prepubescent boys do contain so few immature sperm cells that it would be impossible to do this without actually multiplying them in the lab.
It has also been observed that by isolating particular cells from the tests referred to as endothelial cells, which have been found to be critical in supporting the growth of the immature sperm cells. Efforts have been also made to a cocktail of 5 key proteins thus produced by these endothelial cells that were essential in order to keep the sperm stem cells alive and also replicate them on a long-term basis. Furthermore, tests were conducted on the method in infertile mice and were also able to restore fertility, which has been proven by the male mice that have been fathering pups.
For years, in fact, researchers have indeed been trying to find ways to grow and also expand these cells from testicular biopsies that have been donated by young patients much prior to their cancer treatment, but until now, there has in fact not been a consistently successful approach.
This initial research was done actually on mice and has yet to be proven in humans. Yet, the researchers have indeed hoped that they would be able to take small samples of these immature sperm cells from prepubescent boys undergoing cancer therapy, bulk them up in the lab and than also freeze them for survivors.
Our next step is to determine whether we can re-inject or en graft the expanded sperm-producing stem cells into patients after they are indeed cancer free.
It is but obvious that one would like to retain fertility levels after cancer treatment and too among boys. Men also and so also boys would prefer to keep fertility issues on the low profile.
Contact our Ferty9 experts at best infertility hospitals in hyderabad to get good suggestions about this !

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