IVF – A medicinal boon for couples seeking to reproduce

Reproductive medicine is indeed constantly evolving to improve its success rates. Since the first IVF in 1978, where the egg was fertilized with the sperm in-vitro and then the embryo is transferred to the uterus, millions of parents have welcomed babies using the technology. Here are some technical advances that increase chances of conception.

Pre-Implantation Genetic Screening (PGS):

Going by tradition doctors did select embryos based upon their appearances. However, even top-rated embryos do have chromosomal abnormalities thus resulting in implantation failures. PGS screens embryos that are rather developmentally as well as chromosomally competent, usually genetically normal embryos which are transferred thus increasing the chances of implantation and also reducing miscarriage rates by about half. PGS has been referred to couples who facing failures with IVF/ICSI cycles and women with repeated miscarriages.

Pre Implantation Genetic Diagnosis (PGD):

This does help couples with genetic diseases such as Thalassemia, Spinal muscular dystrophy etc., to have their embryos screened to identify normal embryos without disorders and have them transferred, thus reducing odds of transmitting diseases to their respective children.

IVM (Maturing Immature Eggs in the Lab):

For women with thrombosis or even cancer, IVF/ICSI is not really suitable as hormones are not safe. For these women, IVM is a boon, as either no or even minimal hormones are given. While eggs are still immature they are retrieved and matured in the lab with special techniques before transferring. It is a safe procedure that eliminates the risk factors for IVF.

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